Rhino on Linux?

ok, that makes sense. I’m running a different distro and haven’t encountered most of these issues, but here are packages

wine vkd3d lib32-vkd3d wine-gecko wine-mono dxvk-bin winetricks

and winetricks

winetricks -q corefonts pptfonts dotnet48 vcrun2005 vcrun2010 vcrun2013 vcrun2019 vcrun6 vcrun6sp6 gdiplus dxvk
wine winecfg -v win10
wine Downloads/rhino_en-us_7.32.23221.10241.exe

that worked for me - are they any different from what you’ve tried? If not, could you share console output that wine prints for you (when you run WINEPREFIX=<PREFIX> wine Rhino.exe, so we can troubleshoot further?

The issue with running Rhino in a VM, at lleast with VirtualBox, is that it does not provide direct access to the GPU

that is correct, KVM is able to perform GPU passthrough - are you on a laptop or PC?