I am making great inroads into Layout mode, and have discovered some of the things you mention. Adding new details etc, many detail panes on my layout. all in all GREAT.
One thing I have noticed I used the move or copy option, to retain all the annotations and logos etc, However it denies the ability to alter the view of an active detail. It was perspective and I wanted End, it would not change, had to delete the detail view pane and create new one. Repeatable as well. Sort of defeats the concept of copy does that.
However subject of post is still needed. I currently have to select object, use hammer icon atop layer palette, and find the layer its on, scroll to that layer, my palette is several clicks deep ! ( I wish Show Object layer would auto scroll to it. I can be at that layer and run that command clicking on the hammer (dont think it has a command line wording, else I could hit enter and repeat the command) and it takes me away from it. Then I can turn the layer off in Detail view.
if only OneLayerOff did just that for the active detail, instead ALL the detail views lose visibility of the object.
needs a command OneLayerOffActiveDetail