Indeed, I use custom based on US-International keyboard. However on another computer with the same keyboard layout, I have no such issue with another software that use CTR+ALT+SHIFT+<key> hotkeys (although it’s registered as global hotkey)
So, perhaps windows treat global hotkeys differently than in-application only.
The reason why I’m using these combinations is because they are available and easier to remember like L = line, S = spline, C = circle, etc. and in stupid razer synapsis which doesn’t allow adding labels to commands on buttons it easier to understand what button does what.