Remove duplicate numbers from a list

I have 2 large data sets with many duplicates that i wish to compare but cannot as of right now as they do not line up. I have been searching forums and online looking for a simple way to do this but I cant find one. If anyone could help that’d be great thanks. I’ve attached an image below of the data sets

Create Set

Create Set

3. Attach minimal versions of all the relevant files

Thank you! that worked great