Hi @fbarazi,
Here is what I’ve found on Sklearn and Pandas:
https://stackoverflow.com/questions/16171923/can-scikit-be-used-from-ironpython
https://stackoverflow.com/questions/14432059/can-we-load-pandas-dataframe-in-net-ironpython
NumPy / SciPy support in Rhino 6
So, it doesn’t look good - sorry.
– Dale