I think grasshopper addons can be managed before loading, since most of time users have to install many addons, and they might not use them everyday and some addons are taking lots of time while they are loading.
My suggestion is a new Rhino plugin which is automatically open before Grasshopper loading and asks you to choose what addons should load. It can also has some preset of addons for your specific scripts.
The reason that I share this idea was to develop this idea by members of McNeel Forum
I’m not an expert coder and I’ve some few experiences, but I think this idea could be easily done by just moving the addons from Grasshopper Library folder to somewhere else or simply just block the files by using OS commands on each scripting language.
I think the main challenge is the way that the user interact with the plugin (UI)
I’ve attached a simple sketch of my idea