I have look through some of the criticism, without going too deep into them. I think there is a lot to discuss but even if you take the concept of Scientific Revolutions from Thomas Kuhn, i think you can identify at least some of the features in Wolfram model. You can also see the chapter about the connection with current physics but actually he is confirming current equations in physics through his entire paper. However i am not so entitled to defend it with very specific arguments as I am not a mathematician or physicist but I do see a lot of logic inside that can describe anything that exists. You also have to admit that current accepted physical science especially in quantum theory has come to a point where is kind a running in circles. There are many paradoxes and their explanations don`t make sense so far. Like the particle-wave state, uncertainty principle or entanglement. But even if we accept the criticism i think there is potential at least from a computational and design point of view…