Yes, you can Block a SubD--with symmetry

I find that this is handy when making an object that is going to get moved around a lot. In the case of the steering wheel, using a Blocks allow me to work on the wheel in an axial orientation–yet place it on the angle it lives on.

I moved a node in an obvious way to illustrate that the editing still works.
(Unseen are the point objects and line for snapping to, in the center of the wheel.)