Funny you should ask that, as I've just been looking back through work for past clients to illustrate the point.
Of the past 11 clients that I've produced work for, 8 have had the following as their deliverables (I'm just talking about CAD formats now):
2D Technical drawings of a standard suitable to pass to a supplier for the manufacture of the items in question in PDF and DXF formats (some ask for DWG instead of DXF).
7 of them also asked for 3D CAD files of the assembly in their own format (i.e. the same as the CAD package that they use (typically Inventor, Solidworks etc) OR a cross platform format, so I give them STEP files.
Of the remaining 3 clients, one is a native Rhino user and they only ever want my Rhino files (no need for drawings) and the other two were start-up businesses that didn't have a clue about CAD, so I could have given them something drawn on the back of an envelope and they'd have been none the wiser.
My work covers a very wide range of disciplines from high spec steel helical staircases for large private dwellings, to injection moulded parts, to railway vehicle interiors, to medical equipment to, well, you get the picture. So my output covers a number of different industries; no matter what the sector, a very large percentage of them want 2D drawings - in PDF so that the non-techies in the business have something to look at and clean CAD drawings for them to actually get the stuff made. Because I'm not usually supplying direct to the manufacturer, they want formats that are portable so that they can change suppliers at will and still expect the same product in return. This is why I disagree so strongly with @John_Brock 's assertion that this is a 'specialist' aspect. You can speak the most brilliant language in the world, capable of expressing things that no other language in the world is capable of, but if nobody else can understand you, what's the point? It's all about communication of design and design intent, often to people that you have never met and never will.
I have made production drawings in Rhino that number well into the 1000's. Rhino 4 was the breakthrough that made this viable. Before that, I had to move stuff over to some horrible release of AutoCAD that made my skin crawl every time I used it. On each occasion, going back to Rhino was like coming home. But I have NEVER produced one of these drawings using Layout, because it can't depict things equally in PDF and DXF/DWG formats. Make2D and all of the post process aggravation and clean up that goes with it has been the tool of choice, along with the depths of despair that brings, every time a client asks for a design revision. I would LOVE to be able to use Layouts and the associativity that brings. Because of the above, it's simply not viable. It is the Forbidden Fruit.
If this comes across as an impassioned plea, that's because it is.