That said, I think you can call Rhino from Python and then run it in an automated “head-less” fashion without loading up all of the UI, so you’re sending commands to the instance, ala this topic.
Of course, the commands you’re able to give it include _RunPythonScript, so while it’s two separate instances of the interpreter running, one “outside” and one inside the context of Rhino, that may help you to think about as an option.