Rhino 8 only runs safe mode

When selecting any tool (for example polyline) Rhino 8 crashes. It runs perfectly well in safemode, but I need it to run a certain PlugIn. What would be the necessary steps to find out what the cause of this problem is?

Can you run SystemInfo in Rhino and post the results here?

Thanks so much for your ultrafast reply! But I just installed it on another Device. My workshop-desktop PC might be mor suitable anyway.
Rhino seems quite nice tho!