So many choices. Rhino.inside.revit can extract the analysis model from Revit, along with the 3d geometry and much of the profile and type information useful for analysis: https://www.rhino3d.com/inside/revit/beta/samples/analytical-model-manipulation
The analysis options are endless.
- Karamba is integrated
- Sofistik is an option: https://www.sofistik.de/documentation/2020/en/rhino_interface/grasshopper/index.html
- Oasis, SAP, SCIA can also be connected thru GeometryGym.
- Parastaad is possible https://www.food4rhino.com/app/parastaad
Of course once connected, then optimization can be done: Structural simulation tools for GH?