Hi All,
This is already possible in Rhino 8 to turn a layer off in all details on all layouts.
A more visible or easily discoverable way to do this is on the wish list.
(It will not happen for Rhino 8. Rhino 9 is a possibility when the developers discuss.)
But you can get there in Rhino 8, with a few easy clicks.
Here is more on what @stevefuchs describes above.
HOW TO: TURN Layer Off in ALL DETAILS on ALL LAYOUTS
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Make the Layer (set the new layer off if you want that for future details)
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Go to a layout and make a detail active. ← DO NOT SKIP THIS STEP
This can be a detail that you want the layer ON in or OFF. -
In the Layer panel, scroll the layer you just made.
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Go to the column of Details ON, and right-click on the light bulb icon in the layer row.
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Click ON and IN THIS DETAIL ONLY → ALL LAYOUTS.
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If you also want it OFF in this detail, then click the light blub in the layer row under Details ON to turn it off in the active detail.
See a video on how to do this here with @stevefuchs 3DM.
Hope this helps.
Sincerely,