Interior CFD influece by exterior pressure coefficients

Hi there,

I was wondering if there is a way to combine the effect of an exterior CFD with a series of obstructions in an urban context and an interior CFD influenced by the exterior CFD wind pressure coefficients in the building facades.
Have you done this before? how did you address it? is it required to interpret and modify by hand the discharge coefficient for every window? or the wind factor per facade?

Thanks and sorry for my ignorance in this topic