I just finished a semester teaching Keenan Crane’s Discrete Differential Geometry class, and it left me wanting to implement his whole machinery in Rhino/Grasshopper. Probably the worst way to do this will be in Python, but it’s the language I’m most comfortable with. Should still be possible, since there are some Sparse matrix solvers available through the math.net framework. (See the discussion here: Math.Net function in Python with Rhino for Mac?).
Probably won’t get to this until the Fall, but I’d be happy if someone else did it before me!