Convert 3D scan mesh to one good surface

Hi @Nina
Well, “It depends” is probably the most accurate answer. It depends on how good you are with Rhino, it depends on the geometry, it depends on what other CAD program you plan on using downstream, it depends on the quality of the scan… and probably other factors as well. But short answer is yes, there are plenty of ways to skin that cat. A great discussion here, some older input here - especially the videos at the top.
If you want a more detailed answer, you need to provide more info on your project.
HTH, Jakob