Most applications that are thick with commands, icons, toolsets and palettes, offer the option to easily create custom workspaces.
There is an option to make them with aliases and shortcuts, but that to my thinking is not what computers are for. I am more productive when the process is well defined and simple.
I run off three 23" monitors and I try to get most of what I need to work with (windows and palettes) up on either side of the centre monitor (which I use for the Rhino 4 view or Detailed One view).
And I like to vary the display of palettes, depending on what aspect of construction I am working on i.e modelling, rendering, animating etc.
Is there any chance of making this a simple direct process i.e. photoshop or illustrator as example.